Species Information
The Clostridium difficile 630 genome is 4.30 Million bp long and contains approximately 3982
predicted genes.
Taxonomy: Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium.
Sequencing: The sequence was released 09/20/2006 by the Welcome Trust Sanger Institute, and was described in Nat Genet 38:779-86 (2006) Sebaihia M, Wren BW, Mullany P, Fairweather NF, Minton N, et al.."The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome." Abstract: We determined the complete genome sequence of Clostridium difficile strain 630, a virulent and multidrug-resistant strain. Our analysis indicates that a large proportion (11%) of the genome consists of mobile genetic elements, mainly in the form of conjugative transposons. These mobile elements are putatively responsible for the acquisition by C. difficile of an extensive array of genes involved in antimicrobial resistance, virulence, host interaction and the production of surface... [Click above reference link for full abstract]
Isolation: Isolation publication not available
Sequenced related species/strains: Alkaliphilus metalliredigens QYMF, Alkaliphilus oremlandii OhILAs, Clostridium acetobutylicum ATCC 824, Clostridium beijerinckii NCIMB 8052, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A3 str. Loch Maree, Clostridium botulinum A str. ATCC 19397, Clostridium botulinum A str. Hall, Clostridium botulinum B1 str. Okra, Clostridium botulinum B str. Eklund 17B, Clostridium botulinum E3 str. Alaska E43, Clostridium botulinum F str. Langeland, Clostridium difficile QCD-32g58, Clostridium kluyveri DSM 555, Clostridium novyi NT, Clostridium perfringens str. 13, Clostridium perfringens ATCC 13124, Clostridium phytofermentans ISDg, Clostridium tetani E88, Clostridium thermocellum ATCC 27405
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